Description:Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the developmen t of the ideal SERM-on the complex mechanisms of estrogen action, incl uding ligand-dependent conformational changes in alpha and beta, and t he recruitment of co-activators and co-repressors which modulate the e strogen receptor transcriptional activity and contribute to its crosst alk with growth factor signaling.. The clinical presentation reviews t he data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their e ffects on the reproductive, vascular, skeletal, and central nervous sy stems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology). To get started finding Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology), you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.
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0896039129
Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology)
Description: Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the developmen t of the ideal SERM-on the complex mechanisms of estrogen action, incl uding ligand-dependent conformational changes in alpha and beta, and t he recruitment of co-activators and co-repressors which modulate the e strogen receptor transcriptional activity and contribute to its crosst alk with growth factor signaling.. The clinical presentation reviews t he data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their e ffects on the reproductive, vascular, skeletal, and central nervous sy stems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology). To get started finding Selective Estrogen Receptor Modulators: Research and Clinical Applications (Contemporary Endocrinology), you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.