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Contractile Mechanisms in Muscle (Advances in Experimental Medicine and Biology, 170)

Gerald H. Pollack
4.9/5 (24550 ratings)
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Description:Prior to the emergence of the sliding filament model, contraction theories had been in abundance. In the absence of the kinds of structural and biochemical information available today, it has been a simple matter to speculate about the possible ways in which tension generation and shortening might occur. The advent of the sliding filament model had an immediate impact on these theories; within several years they fell by the wayside, and attention was redirected towards mechanisms by which the filaments might be driven to slide by one another. In terms of identifying the driving mechanism, the pivotal observa tion was the electron micrographic indentification of cross-bridges extending from the thick filaments. It was quite naturally assumed that such bridges, which had the ability to split ATP, were the molecular motors, i.e., that they were the sites of mechanochemical transduction. Out of this presumption grew the cross-bridge model. in which filament sliding is presumed to be driven by the cyclic interaction of cross-bridges with complementary actin sites located along the thin filaments.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Contractile Mechanisms in Muscle (Advances in Experimental Medicine and Biology, 170). To get started finding Contractile Mechanisms in Muscle (Advances in Experimental Medicine and Biology, 170), you are right to find our website which has a comprehensive collection of manuals listed.
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PDF, EPUB & Kindle Edition
Publisher
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ISBN
146844705X

Contractile Mechanisms in Muscle (Advances in Experimental Medicine and Biology, 170)

Gerald H. Pollack
4.4/5 (1290744 ratings)
Read Now Download now ⏭ listen AudioBook
Description: Prior to the emergence of the sliding filament model, contraction theories had been in abundance. In the absence of the kinds of structural and biochemical information available today, it has been a simple matter to speculate about the possible ways in which tension generation and shortening might occur. The advent of the sliding filament model had an immediate impact on these theories; within several years they fell by the wayside, and attention was redirected towards mechanisms by which the filaments might be driven to slide by one another. In terms of identifying the driving mechanism, the pivotal observa tion was the electron micrographic indentification of cross-bridges extending from the thick filaments. It was quite naturally assumed that such bridges, which had the ability to split ATP, were the molecular motors, i.e., that they were the sites of mechanochemical transduction. Out of this presumption grew the cross-bridge model. in which filament sliding is presumed to be driven by the cyclic interaction of cross-bridges with complementary actin sites located along the thin filaments.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Contractile Mechanisms in Muscle (Advances in Experimental Medicine and Biology, 170). To get started finding Contractile Mechanisms in Muscle (Advances in Experimental Medicine and Biology, 170), you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.
Pages
—
Format
PDF, EPUB & Kindle Edition
Publisher
—
Release
—
ISBN
146844705X

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